Avicenna Journal of Neuro Psych Physiology Avicenna Journal of Neuro Psych Physiology Avicenna J Neuro Psych Physio http://www.avicennajnpp.com 2383-2436 2383-2444 10.5812/ajnpp. en jalali 2017 6 24 gregorian 2017 6 24 3 1
en 10.17795/ajnpp-37911 Factors Affecting the Risk of Mental Disorders in Patients With Bipolar Disorder in the West of Iran Factors Affecting the Risk of Mental Disorders in Patients With Bipolar Disorder in the West of Iran research-article research-article Background

Drug addiction, obsessive compulsive disorders (OCD), and other anxiety disorders are the disorders most commonly found in patients with bipolar disorder.

Objectives

The purpose of this study was to identify the factors affecting the risk of drug addiction, obsessive compulsive disorders, and other anxiety disorders in patients with bipolar disorder.

Patients and Methods

In this retrospective cohort study, the medical records of 400 patients with bipolar disorder hospitalized in Hamadan, Iran, between 2008 and 2014 were examined. Patient information, including demographic characteristics and comorbidity, was collected. A data analysis was performed using a separate logistic regression for each disorder. The statistical package used was STATA software version 11. A P-value of less than 0.05 was considered statistically significant.

Results

The mean (SD) age of the patients with bipolar disorder was 34.62 (1.68) years. Of the 400 patients with bipolar disorder, 135 (33.75%) patients had anxiety disorders, 67 (16.8%) patients suffered from drug addiction, and 45 (11%) patients had OCD. An association was established between drug addiction and OCD, and gender (P ≤ 0.05). The ORs of anxiety disorders, drug addiction, and OCD were 1.05 (95% CI = 0.65 - 1.68), 0.26 (95% CI = 0.10 - 0.63), and 2.33 (95% CI = 1.21 - 4.48) for women, and 0.92 (95% CI = 0.52 - 2.13), 3.01 (95% CI = 1.64 - 5.55), and 0.64 (95% CI = 0.25 - 1.62) for the patients who smoked, respectively. In addition, there was no significant association between the different disorders and age, marital status, history of relapse, and history of suicide.

Conclusions

The results showed that there was a greater risk of anxiety disorders with bipolar disorder than other disorders. While women with bipolar disorder were at higher risk of anxiety disorders and OCD, men were at greater risk of drug addiction.

Background

Drug addiction, obsessive compulsive disorders (OCD), and other anxiety disorders are the disorders most commonly found in patients with bipolar disorder.

Objectives

The purpose of this study was to identify the factors affecting the risk of drug addiction, obsessive compulsive disorders, and other anxiety disorders in patients with bipolar disorder.

Patients and Methods

In this retrospective cohort study, the medical records of 400 patients with bipolar disorder hospitalized in Hamadan, Iran, between 2008 and 2014 were examined. Patient information, including demographic characteristics and comorbidity, was collected. A data analysis was performed using a separate logistic regression for each disorder. The statistical package used was STATA software version 11. A P-value of less than 0.05 was considered statistically significant.

Results

The mean (SD) age of the patients with bipolar disorder was 34.62 (1.68) years. Of the 400 patients with bipolar disorder, 135 (33.75%) patients had anxiety disorders, 67 (16.8%) patients suffered from drug addiction, and 45 (11%) patients had OCD. An association was established between drug addiction and OCD, and gender (P ≤ 0.05). The ORs of anxiety disorders, drug addiction, and OCD were 1.05 (95% CI = 0.65 - 1.68), 0.26 (95% CI = 0.10 - 0.63), and 2.33 (95% CI = 1.21 - 4.48) for women, and 0.92 (95% CI = 0.52 - 2.13), 3.01 (95% CI = 1.64 - 5.55), and 0.64 (95% CI = 0.25 - 1.62) for the patients who smoked, respectively. In addition, there was no significant association between the different disorders and age, marital status, history of relapse, and history of suicide.

Conclusions

The results showed that there was a greater risk of anxiety disorders with bipolar disorder than other disorders. While women with bipolar disorder were at higher risk of anxiety disorders and OCD, men were at greater risk of drug addiction.

Anxiety Disorders;Bipolar Disorder;Comorbidity;Drug Addiction;Obsessive Compulsive Disorder;Logistic Regression Anxiety Disorders;Bipolar Disorder;Comorbidity;Drug Addiction;Obsessive Compulsive Disorder;Logistic Regression http://www.avicennajnpp.com/index.php?page=article&article_id=37911 Roya Najafi Vosough Roya Najafi Vosough Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran Ali Ghaleiha Ali Ghaleiha Behavioral Disorders and Substance Abuse Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran Behavioral Disorders and Substance Abuse Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran Javad Faradmal Javad Faradmal Modeling of Noncommunicable Disease Research Canter, Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran Modeling of Noncommunicable Disease Research Canter, Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran Hossein Mahjub Hossein Mahjub Research Center for Health Sciences and Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran; Research Center for Health Sciences and Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran. Tel: +98-8138380025, Fax: +98-8138380509 Research Center for Health Sciences and Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran; Research Center for Health Sciences and Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran. Tel: +98-8138380025, Fax: +98-8138380509